2000年和2003年在沈阳农业大学获得农学学士和硕士学位，2006年在中国科学院植物研究所获得理学博士学位，毕业后留所工作至今，2018年晋升为研究员。2015年入选中国科学院青年创新促进会，2017年获国家自然科学基金委优秀青年基金资助，2019年被评为中国科学院青年创新促进会优秀会员，同年获得中国植物病理学会青年植物病理学家奖，2024年当选中国植物病理学会会士。现任中国植物病理学会产后病理学专业委员会副主任、中国园艺学会采后科学技术分会副秘书长，曾任中国科学院青年创新促进会秘书长（2019-2021）。

主持国家自然科学基金委优秀青年基金1项，国际合作项目1项，面上项目3项，青年基金1项，国家重点研发计划课题1项、子课题2项，中国科学院重点部署项目课题1项。发表论文130余篇，累计引用4500余次。其中，以通讯作者和第一作者（含并列）在Comprehensive Reviews in Food Science and Food Safety、Journal of Hazardous Materials、New Phytologist、Food Chemistry、Environmental Microbiology、Postharvest Biology and Technology、Molecular Plant-Microbe Interaction等期刊发表SCI论文33篇；获得省部级奖励8项；获得授权国家发明专利15项。担任Postharvest Biology and Technology、Biological Control、Horticulturae、未来食品科学、微生物学报等学术期刊的编委及科技智库期刊《中国科学院院刊》首届青年编委。

主要研究方向和内容：

1）果实采后病害发生的分子机制及控制技术

以青霉病等果实采后主要病害为研究对象，揭示微生物组、寄主和环境之间互作的分子网络，鉴定调控病原菌致病力和寄主抗病性的关键因子；筛选高活性靶向抑菌物质，研发采后病害新型控制技术和产品。

2）真菌毒素生物合成的分子基础及污染控制技术

以棒曲霉素等果蔬产品重要真菌毒素为研究对象，解析真菌毒素生物合成和转运的分子途径，鉴定影响真菌毒素合成的内、外源关键因子，建立分子调控网络；筛选降解真菌毒素的微生物菌株，鉴定高效降解真菌毒素的生物酶；通过定向进化、分子改造等方法提升降解效率，研制商业化应用的真菌毒素降解酶制剂。

主持和参加的科研项目：

1. “果实腐烂过程中代谢标志物的生物合成调控及与质量安全的关联机制”，国家自然科学基金国际(地区)合作与交流项目（32261133624，2023.01-2025.12），主持人。
2. “生鲜农产品产后供应链品质与环境关联机制”，十四五国家重点研发计划课题（2021YFD2100501，2021.12-2026.11），主持人。
3. “组蛋白甲基化修饰调控扩展青霉棒曲霉素生物合成的分子机制”，国家自然科学基金面上项目（32072273，2021.01-2024.12），主持人。
4. “中国科学院青年创新促进会优秀会员”，中国科学院人才项目（Y201919，2020.01-2022.12），主持人。
5. “植物源食品采后生物学基础”，国家自然科学基金优秀青年基金（31722043，2018.01-2020.12），主持人。
6. “高值特色果蔬冷链物流及包装技术研发示范——猕猴桃物流防腐保鲜技术研发和示范”，十三五国家重点研发计划子任务（2018YFD0401303-2，2018.07-2020.12），主持人。
7. “果蔬采后质量与品质控制关键技术研究及装备开发——病原真菌毒素合成的分子基础和转运途径研究”，十三五国家重点研发计划子任务（2016YFD0400902，2016.07-2020.12），主持人。
8. “果实采后病原真菌分泌组的N-糖基化修饰分析和调控机制研究”，国家自然科学基金面上项目（31371863，2014.01-2017.12），主持人。
9. “高值特色果实采后品质安全的防控技术”，中国科学院重点部署项目课题，（KFZD-SW-102-5，2016.01-2016.12），主持人。
10. “中国科学院青年创新促进会”，中国科学院人才项目（2015063，2015.10-2018.12），主持人。
11. “环境pH对果实采后病原真菌致病力的影响和调控机制研究”，国家自然科学基金面上项目（31171765，2012.01-2015.12），主持人。
12. “酵母拮抗菌与果实采后病原真菌细胞间的互作机制研究”，国家自然科学基金青年基金（30700553，2008.01-2010.12），主持人。

研究论文（^#同等贡献；^*通讯作者）

2024

Zhuo RL, Zhang XK, Chen Y, Xing MY, Tian SP, Li BQ*, 2024. 3-hydroxycoumarin effectively inhibits development and pathogenicity by targeting Pempk proteins of Penicillium expansum. Postharvest Biology and Technology. 214: 112987.

Xu XD^#, Chen Y^#, Zhang ZQ, Chen T, Li BQ*, Tian SP*. 2024. Set1/COMPASS regulates growth, pathogenicity, and patulin biosynthesis of Penicillium expansum via H3K4 methylation and the interaction with PeVelB. Journal of Advanced Research. 62: 47-57.

2023

Shen Y, Li XN, Xiong R, Ni Y, Tian SP, Li BQ*. 2023. Effect of peach trichome removal on post-harvest brown rot and on the fruit surface microbiome. International Journal of Food Microbiology. 402: 110299.

Chen Y^#, Xing MY^#, Chen T, Tian SP, Li BQ*. 2023. Effects and mechanisms of plant bioactive compounds in preventing fungal spoilage and mycotoxin contamination in postharvest fruits: a review. Food Chemistry. 415: 135787.

Xing MY^#, Chen Y^#, Dai WQ, He X, Li BQ*, Tian SP*. 2023. Immobilized short-chain dehydrogenase/reductase on Fe₃O₄ particles acts as a magnetically recoverable biocatalyst component in patulin bio-detoxification system. Journal of Hazardous Materials. 448: 130986.

Zhuo RL^#, Li GJ^#, Peng HM, Zong YY, Wang X, Lu SS, Chen Y, Zhang ZQ, Tian SP, Li BQ*. 2023. Extensive regulation of pH-responsive transcription factor PacC on secondary metabolism contributes to development and virulence of Botrytis cinerea. Postharvest Biology and Technology. 197: 112219.

Zhuo RL, Chen Y, Xing MY, Zhang ZQ, Tian SP, Li BQ*. 2023. Ena proteins respond to PacC-mediated pH signaling pathway and play a crucial role in patulin biosynthesis. Journal of Fungi. 9: 806.

Chen Y, Zhang YC, Xu DY, Zhang ZQ, Li BQ*, Tian SP*. 2023. PeAP1-mediated oxidative stress response plays an important role in the growth and pathogenicity of Penicillium expansum. Microbiology Spectrum, 11: e0380822.

Liu T, Chen Y, Tian SP, Li BQ*. 2023. Crucial roles of effectors in interactions between horticultural crops and pathogens.Horticulturae. 9, 250.

2022

Chen Y, Zhang ZQ, Tian SP, Li BQ*.2022. Application of -omic technologies in postharvest pathology: Recent advances and perspectives. Current Opinion in Food Science. 45:100820.

Xing MY, Chen Y, Li BQ*, Tian SP*. 2022. Highly efficient removal of patulin using immobilized enzymes of Pseudomonas aeruginosa TF-06 entrapped in calcium alginate beads. Food Chemistry. 377, 131793.

Zhuo RL, Li BQ*, Tian SP. 2022. Alginate oligosaccharide improves resistance to postharvest decay and quality in kiwifruit (Actinidia deliciosa cv. Bruno). Horticultural Plant Journal. 8, 44-52.

Li BQ, Chen Y, Tian SP*. 2022.Function of pH-dependent transcription factor PacC in regulating development, pathogenicity, and mycotoxin biosynthesis of phytopathogenic fungi. The FEBS Journal. 289, 1723-1730.

2021

Xing MY, Chen Y, Li BQ*, Tian SP*. 2021. Characterization of a short-chain dehydrogenase/reductase and its function in patulin biodegradation in apple juice. Food Chemistry. 348, 129046.

Chen Y, Zhang ZQ, Li BQ*, Tian SP*. 2021. PeMetR-mediated sulfur assimilation is essential for virulence and patulin biosynthesis in Penicillium expansum. Environmental Microbiology. 23, 5555-5568.

Xia YX, Zhuo RL, Li BQ*, Tian SP. 2021. Effects of 1-methylcyclopropene on disease resistance of red-fleshed kiwifruit during long-term cold storage and the possible mechanisms. New Zealand Journal of Crop and Horticultural Science. 49, 182-195.

2020

Li BQ^#, Chen Y^#, Zhang ZQ, Qin GZ, Chen T, Tian SP*. 2020. Molecular basis and regulation of pathogenicity and patulin biosynthesis in Penicillium expansum. Comprehensive Reviews in Food Science and Food Safety. 19, 3416-3438.

Xing MY^#, Li BQ^#, Chen Y, Tian SP*. 2020. Ribonucleoside diphosphate reductase plays an important role in patulin degradation by Enterobacter cloacae subsp. dissolvens. Journal of Agricultural and Food Chemistry. 68, 5232-5240.

Zhang XK^#, Li BQ^#, Zhang ZQ, Chen Y, Tian SP*. 2020. Antagonistic yeast: a promising alternative to chemical fungicides for controlling postharvest diseases of fruit. Journal of Fungi. 6, 158.

2019

Li BQ^#, Chen Y^#, Zong YY^#, Shang YJ, Zhang ZQ, Xu XD, Wang X, Long MY, Tian SP*. 2019. Dissection of patulin biosynthesis, spatial control and regulation mechanism in Penicillium expansum. Environmental Microbiology. 21: 1124-1139.

2018

Chen Y^#. Li BQ^#, Xu XD, Zhang ZQ, Tian SP*. 2018. The pH-responsive PacC transcription factor plays pivotal roles in virulence and patulin biosynthesis in Penicillium expansum. Environmental Microbiology. 20: 4063-4078.

郑剑, 蒋镇烨, 戚雯烨, 潘洁, 郑小林*, 李博强*. 2018. 伞形花内酯处理对美味猕猴桃果实品质和青霉病抗性的影响. 园艺学报. 45(04): 734-742.

王晓, 徐晓迪, 陈勇, 卓瑞玲, 田世平, 李博强*. 2018. 宁夏枸杞鲜果采后病原菌的分离、鉴定及水杨酸的抑病效果研究. 食品安全质量检测学报. 9(22): 5837-5842.

2017

Chen Y, Peng HM, Wang X, Li BQ*, Long MY, Tian SP. 2017. Biodegradation mechanisms of patulin in Candida guilliermondii: an iTRAQ-based proteomic analysis. Toxins. 9: E48.

Li BQ, Xia YX, Wang YY, Qin GZ, Tian SP*. 2017. Characterization of genes encoding key enzymes involved in anthocyanin metabolism of kiwifruit during storage period. Frontiers in Plant Science. 8:341.

李博强，陈 勇，徐小迪，王晓，田世平*. 2017. 棒曲霉素的生物合成、调控机制及其控制技术研究进展. 食品安全质量检测学报. 8(9): 3283-3288.

2016

An B#, Li BQ#, Li H, Zhang ZQ, Qin GZ, Tian SP*. 2016. Aquaporin8 regulates cellular development and reactive oxygen species production, a critical component of virulence in Botrytis cinerea. New Phytologist. 209: 1668-1680.

Li BQ, Peng HM, Tian SP*. 2016. Attachment capability of antagonistic yeast Rhodotorula glutinis to Botrytis cinerea contributes to biocontrol efficacy. Frontiers in Microbiology. 7:601.

2015及以前

Li BQ^#, Zong YY^#, Du ZL, Chen Y, Zhang ZQ, Qin GZ, Zhao WM, Tian SP*. 2015. Genomic characterization reveals insights into patulin biosynthesis and pathogenicity in Penicillium species. Molecular Plant–Microbe Interactions. 28: 635-647.（封面文章）

Li BQ, Wang WH, Zong YY, Qin GZ, Tian SP*. 2012. Exploring pathogenic mechanisms of Botrytis cinerea secretome under different ambient pH based on comparative proteomic analysis. Journal of Proteome Research. 11: 4249-4260.

Li BQ^#, Zhang CF^#, Cao BH, Qin GZ, Wang WH, Tian SP*. 2012. Brassinolide enhances cold stress tolerance of fruit by regulating plasma membrane proteins and lipids. Amino acids. 43: 2469-2480.

Shi XQ^#, Li BQ^#, Qin GZ, Tian SP*. 2012. Mechanism of antifungal action of borate against Colletotrichum gloeosporioides related to mitochondrial degradation in spores. Postharvest Biology and Technology. 67: 138-143.

Li BQ^#, Lai TF^#, Qin GZ, Tian SP*. 2010. Ambient pH stress inhibits spore germination of Penicillium expansum by impairing protein synthesis and folding: a proteomic-based study. Journal of Proteome Research. 9: 298-307.

Li BQ, Zhou ZW, Tian SP*. 2008. Combined effects of endo- and exogenous trehalose on stress tolerance and biocontrol efficacy of two antagonistic yeasts.Biological Control. 46: 187-193.

Li BQ, Tian SP*. 2007. Effect of intracellular trehalose in Cryptococcus laurentii and exogenous lyoprotectants on its viability and biocontrol efficacy on Penicillium expansum in apple fruit. Letters in Applied Microbiology. 44: 437-442.

Li BQ,Tian SP*. 2006. Effects of trehalose on stress tolerance and biocontrol efficacy of Cryptococcus laurentii. Journal of Applied Microbiology. 100: 854-861.