The E3 Ligase AtRDUF1 Positively Regulates Salt Stress Responses in Arabidopsis thaliana
作 者：Li JH, Han YY, Zhao QZ, Li CH, Xie Q, Chong K, Xu YY*
影响因子：4.092
刊物名称：PLoS One
出版年份：2013
卷：8 期：8 页码：e71078
论文摘要：
Ubiquitination is an important post-translational protein modification that is known to play critical roles in diverse biological processes in eukaryotes. The RING E3 ligases function in ubiquitination pathways, and are involved in a large diversity of physiological processes in higher plants. The RING domain-containing E3 ligase AtRDUF1 was previously identified as a positive regulator of ABA-mediated dehydration stress response inArabidopsis. In this study, we report that AtRDUF1 is involved in plant responses to salt stress.AtRDUF1expression is upregulated by salt treatment. Overexpression ofAtRDUF1inArabidopsisresults in an insensitivity to salt and osmotic stresses during germination and seedling growth. A double knock-out mutant ofAtRDUF1and its close homologAtRDUF2(atrduf1atrduf2) was hypersensitive to salt treatment. The expression levels of the stress-response genesRD29B,RD22, andKIN1are more sensitive to salt treatment inAtRDUF1overexpression plants. In summary, our data show thatAtRDUF1positively regulates responses to salt stress inArabidopsis.
