姓  名: 李萌
职务/职称: 研究员
联系电话: (86)-010-62836692
电子邮件: limco2@ibcas.ac.cn
个人网页: http://www.klpbcas.com/yjzcy/hf_71485/
课 题 组: 光合作用代谢调控机制研究组
李萌,男,博士,研究员,博士生导师。

中国科学院植物研究所研究员,博士生导师。2010年在中国农业大学获得生物科学学士学位,2016年在田纳西大学诺克斯维尔分校获得博士学位。在攻读博士学位期间辅修Bredesen中心能源科学与工程专业方向。2016-2019年在华盛顿州立大学生物化学研究所进行博士后研究,2019-2023年先后以博士后及研究科学家身份在华盛顿大学(西雅图)海洋学院开展研究工作。2022-2023年在华盛顿大学完成数据科学 (Data Science) 专业培训。20237月到中国科学院植物研究所工作。围绕光合作用的光保护机理、暗反应碳浓缩机理,以蓝细菌、硅藻、高等植物等不同进化进程的产氧光合生物为对象,开展了系统研究。在Nature Plants, The Plant Cell, Photosynthesis Research, RSC Advances等国际期刊上发表相关论文论著共计18篇。

主要研究方向

1)光合作用光-暗偶联调控机理

以光合作用光能转换的物质能量偶联和 CO2浓缩机制 (CCM) 的分子机制为切入点,系统地研究光反应与暗反应的量化偶联调控机理。注重数学计算模型与量化实验数据的相互促进和补充,同时利用数据科学(流行说法人工智能)等其他学科研究工具,促进光合作用研究的前沿发展、展开面向未来的应用基础研究。

2)基于光合作用机理的育种设计及应用

考虑光合生物实际环境条件(如波动的光强、温度等),为大豆和苜蓿等农牧作物的高产种质设计及能源气候等问题提供基于光合作用机理的解决方案。

研究论文 (#标记为共同第一作者;*标记为通讯作者)

2023

Li M, Young JN (2023) Temperature sensitivity of carbon concentrating mechanisms in the diatom Phaeodactylum tricornutum. Photosynth Res., 156: 205–215. https://doi.org/10.1007/s11120-023-01004-2

Garcia AK, Kędzior M, Taton A, Li M, Young JN, Kaçar B. (2023) Effects of RuBisCO and CO2 concentration on cyanobacterial growth and carbon isotope fractionation. Geobiology, 21(3): 390-403. https://doi.org/10.1111/gbi.12543

2022

Kędzior M, Garcia AK, Li M, Taton A, Adam ZR, Young JN, Kaçar B. (2022) Resurrected Rubisco suggests uniform carbon isotope signatures over geologic time. Cell Reports, 39 (4), 110726 https://doi.org/10.1016/j.celrep.2022.110726

Semchonok DA, Mondal J, Cooper CJ, Schlum K, Li M, Amin M, Sorzano COS, Ramírez- Aportela E, Kastritis P, Boekema EJ, Guskov A, Bruce BD. (2022) Cryo-EM Structure of a Tetrameric Photosystem I from Chroococcidiopsis TS-821, a Thermophilic, Non-heterocyst-forming Cyanobacteria. Plant Communications,3 (1), 100248.https://doi.org/10.1016/j.xplc.2021.100248.

2021

Li M, Svoboda V, Davis G, Kramer D, Kunz HH, Kirchhoff H. (2021) Impact of ion fluxes across thylakoid membranes on photosynthetic electron transport and photoprotection. Nature Plants, 7: 979–988. https://doi.org/10.1038/s41477-021-00947-5

2020

Li M#, Mukhopadhyay R#, Svoboda V, Oung HO, MullendoreDL, Kirchhoff H. (2020) Measuring the dynamicity of thylakoid architecture in plant tissue by electron microscopy. Plant Direct, 00:1–14. https://doi.org/10.1002/pld3.280

Höhner R, Pribil M, Herbstová M, Lopez LS, Kunz HH, Li M, Wood M, Svoboda V, Puthiyaveetil M, Leister D, Kirchhoff H. (2020) Plastocyanin is the long-range electron carrier between photosystem II and photosystem I in plants. PNAS,117 (26), 15354-15362.

2019

Li M, Calteau A, Semchonok D, Witt T, Nguyen J, Sassoon N, Boekema EJ, Whitelegge J, Gugger M, Bruce BD. (2019) Physiological and Evolutionary Implications of Tetrameric Photosystem I in Cyanobacteria. Nature Plants, 5: 1309–1319. https://doi.org/10.1038/s41477-019-0566-x

Brady NG#, Li M#, Ma Y, Gumbart JC, Bruce BD. (2019)Non-detergent isolation of a cyanobacterial photosystem I using styrene maleic acid alternating copolymers. RSC Advances, 9 (54), 31781-31796

Schneider D, Lopez LS, Li M, Crawford JD, Kirchhoff H, Kunz H. (2019) Fluctuating light experiments and semi-automated plant phenotyping enabled by self-built growth racks and simple upgrades to theIMAGING-PAM. Plant Methods, volume 15: 156.

2018

Shelaev IV, Mamedov MD, Gostev FE, Aybush AV, Li M, Nguyen J, Bruce BD, Nadtochenko VA. (2018) Comparisons of Electron Transfer Reactions in a Cyanobacterial Tetrameric and Trimeric Photosystem I Complexes. Photochem Photobiol, doi: 10.1111/php.12886.

Koochak H, Puthiyaveetil S, Mullendore D, Li M, Kirchhoff, H. (2018) The structural and functional domains of plant thylakoid membranes. The Plant Journal, https://doi.org/10.1111/tpj.14127.

2017

Kirchhoff H, Li M, Puthiyaveetil S. (2017) Sublocalization of Cytochrome b6f Complexes in Photosynthetic Membranes. Trends Plant Sci., 2017 Jul;22(7):574-582.

2016

Semchonok DA, Li M, Bruce BD, Oostergetel GT, Boekema EJ. (2016) Cryo-EM structure of a tetrameric cyanobacterial photosystem I complex reveals novel subunit interactions. BBA -Bioenergetics, 1857(9), 1619-1626.

2014

Li M, Semchonok DA, Boekema EJ, Bruce BD. (2014) Characterization and Evolution of Tetrameric Photosystem I from the Thermophilic Cyanobacterium Chroococcidiopsis sp. TS-821. The Plant Cell, 26(3): 1230–1245.

Baker DR, Manocchi AK, Lamicq ML, Li M, Nguyen K, Sumner JJ, Bruce BD, Lundgren CA. (2014) Comparative Photoactivity and Stability of Isolated Cyanobacterial Monomeric and Trimeric Photosystem I. J. Phys. Chem. B, 118 (10), pp 2703–2711

2013

Liang Y, Tan ZM, Zhu L, Niu QK, Zhou JJ, Li M, Chen LQ, Zhang XQ, Ye D. (2013) MYB97, MYB101 and MYB120 Function as Male Factors That Control Pollen Tube-Synergid Interaction in Arabidopsis thaliana Fertilization. PLoS Genet., 9(11): e1003933

专著:

Koochak H, Li M, Kirchhoff H. (2017) Chapter 10: Thylakoid Membrane Dynamics in Higher Plants. Photosynthesis and Bioenergetics: pp. 221-242.