“植物生物学论坛”系列讲座—69

报告题目:The guidance of plant growth by auxin and beyond
报告人:Klaus Palme
    Center of Biosystems Analysis, The Albert-Ludwigs-University of Freiburg, Germany
报告时间:2010年11月4日 15:00
报告地点:实验楼报告厅
联系人:刘春明研究员(cmliu@ibcas.ac.cn)
报告人简历请见附件。
欢迎广大师生光临。
Dr. Klaus Palme is a Professor in Molecular Plant Physiology at Freiburg University′s Faculty of Biology. His lab pioneered plant hormone action and signaling and developed innovative technologies to unravel the spatial and temporal dynamics of signaling processes. He molecularly characterized the first receptors for the plant hormone auxin and elucidated the basic principles of auxin transport. This led, for example, to the identification and subsequent structural and functional characterization of the PIN auxin efflux carrier proteins. His team developed innovative techniques for imaging and high-throughput cellome studies. This allowed to unravel the PIN interaction network which was shown to be represented in dynamic nano-environments.
As systems biology demands quantitative, comprehensive data, which need to be mapped into the three-dimensional landscape of cells, tissues and organs, a robust three-dimensional (3D) digital atlas of cellular components in any postembryogenic stage needs to be developed. Such an atlas will have important applications by providing previously unavailable knowledge on cellular characteristics and allow high-throughput analysis of cellular information at single cell resolution. A platform for building three-dimensional (3D) computational models of roots was recently developed by the Palme team. The intrinsic Root Coordinate System was developed as a reference model for the root apical meristem to annotate cells according to their location, type, and division status. This enabled the direct quantitative comparison between roots at single cell resolution, and was able to incorporate any recognizable feature. Applications and innovative opportunities arising from this technological advance will be discussed. Discoveries made by Dr. Palme were published in high impact journals like Science, Nature, Cell, PNAS and others.
 
 
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